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Moving Beyond the Worklist: Why Agentic AI Is Radiology’s Next Efficiency Leap

Guest Article by Angela Adams, RN in HIT Consultant

December 15, 2025 | Agentic AI is moving radiology beyond the worklist by automating follow-ups, enriching reads with clinical context, and improving reliability and outcomes.

Radiology is being asked to do more with less. Agentic AI offers a new path by moving beyond static worklists to autonomous agents that handle follow-ups, enrich radiologists’ reads with clinical context, and coordinate care end to end. This approach reduces manual burden, improves reliability, prevents patients from being lost to follow-up, and helps health systems deliver better outcomes in a constrained environment.

Radiology is in an everlasting do-more-with-less era. Payment rates continue to tighten, operating costs keep climbing, and workforce shortages are stretching teams to their limits. Yet expectations for speed, accuracy, and reliability have never been higher.

For years, radiology departments have tried to manage this tension with worklists. These lists track patients who need follow-up, outreach, scheduling, or additional care. On paper, they create visibility. In practice, they often become long, manual to-do lists that rely on already overburdened humans to keep care moving forward.

That model is starting to break.

Agentic AI offers a fundamentally different approach. Instead of simply tracking work for people to complete, AI agents can actually perform the grunt work that distracts from care. This shift has major implications for efficiency, reliability, and patient outcomes across radiology operations.

From Task Tracking to Task Execution

Traditional automation in healthcare stops at alerts and reminders. A follow-up recommendation is flagged. A task appears on a list. A human must still act.

Agentic AI goes further. These systems can identify patients due for follow-up, prioritize them by clinical urgency, and autonomously initiate next steps. That might include reaching out to patients, preparing pre-authorization documentation, or coordinating scheduling without adding new tasks to staff workflows.

The goal is simple but powerful. Take work off human plates rather than redistributing it. And do it in a way that is trustworthy and highly reliable.

In an environment where health system leaders are bracing for budget constraints and tighter headcount, technologies that remove labor-intensive steps while improving reliability are no longer optional.

Closing the Radiology Context Gap

One of the most overlooked challenges in radiology is the lack of clinical context available at the time of interpretation. Radiologists are often asked to read studies with minimal background information, particularly in teleradiology settings where access to the full electronic health record may be limited.

Without context, reports tend to hedge. Recommendations become vague. Follow-up guidance may lack specificity.

Agentic AI can help bridge this gap by automatically pulling relevant clinical history, prior imaging, symptoms, and risk factors from the EHR and presenting a concise summary before the read. With that information at hand, radiologists can generate clearer, more actionable impressions and recommendations.

Better context leads to better reads. Better reads lead to better downstream care.

Automating Follow-Up End to End

The real power of agentic AI emerges after the report is finalized.

Once a follow-up recommendation is detected, AI agents can orchestrate the entire downstream process. One agent can determine whether a new order or authorization is required and prepare payer-specific submissions. Another can contact the patient to explain the next steps and begin scheduling. A conversational agent can answer common questions in plain language and escalate to a human when clinical judgment is needed.

This creates an automated safety net around follow-up care. Every recommendation is captured. Every patient is informed. Every step is carried through to completion.

The result is fewer patients lost to follow-up, reduced liability risk, and improved revenue capture by preventing leakage and missed conversions.

Making Opportunistic Screening Reliable

Agentic AI also opens the door to making opportunistic screening routine rather than risky.

Incidental findings such as coronary artery calcifications or low bone density often go underutilized because of concerns about follow-up reliability and liability. AI agents can change that by ensuring these findings are contextualized, communicated, and acted upon consistently.

When an incidental finding is flagged, an agent can gather relevant risk factors from the record, support a tailored recommendation, notify the appropriate care team, and assist with referrals. What once felt like a liability becomes a proactive care opportunity that benefits both patients and health systems.

Cutting Through the AI Hype

As interest in agentic AI grows, it is important to separate real solutions from hype. Legacy systems often move too slowly to support meaningful change, while some new entrants promise more than they can deliver.

The right approach focuses on outcomes. Does the technology actually reduce manual work? Does it improve follow-up reliability? Does it integrate into existing workflows rather than forcing change?

Radiology’s next efficiency leap will not come from more dashboards or longer worklists. It will come from intelligent automation that quietly, reliably gets the work done.

Agentic AI offers a path forward where every follow-up is captured, every patient is supported, and clinicians can spend less time managing tasks and more time delivering care.

Read Angela’s full article in HIT Consultant here.